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Case number:094
Clinical presentation:Woman aged 70 years with left breast carcinoma who underwent left MRM in 1994. She presented in 2015 with right breast serous nipple discharge. The nipple discharge is occasional, serous for 1 year, with one episode of blood-stained discharge 1 day ago.


Breast composition:ACR category b (there are scattered areas of fibroglandular density)
Mammography features:

 ‣ Location of the lesion:Right breast
 ‣ Mass:
   • Number:0
   • Size:None
   • Shape:None
   • Margins:None
   • Density:None
 ‣ Calcifications:
   • Typically benign:Round, vascular
   • Suspicious:None
   • Distribution:None
 ‣ Architectural distortion:None
 ‣ Asymmetry:None
 ‣ Intramammary node:None
 ‣ Skin lesion:None
 ‣ Solitary dilated duct:None
 ‣ Associated features:None


Ultrasound features: Right breast, lower inner quadrant at 4 o’clock

 ‣ Mass
   • Location:Right breast, lower inner quadrant at 4 o’clock
   • Number:1
   • Size:0.1 cm within dilated duct
   • Shape:Round
   • Orientation:Parallel
   • Margins:Circumscribed
   • Echo pattern:Isoechoic
   • Posterior features:No posterior features
 ‣ Calcifications:None
 ‣ Associated features:Duct changes
 ‣ Special cases:Solitary dilated duct


BI-RADS Category: 4B (moderate suspicion of malignancy)

Further assessment:

Further assessment advised: Further imaging with breast MRI


MRI features:
 ‣ MRI features:Amount of fibroglandular tissue: ACR category a (the breasts are almost entirely fatty). Background parenchymal enhancement: Minimal (< 25%), symmetrical

 ‣ Location:Right breast at 3 o’clock
 ‣ Focus:No
 ‣ Mass:
   • Shape:Tiny linear
   • Margin: Circumscribed
   • Internal enhancement:Homogeneous
   • Kinetic curve:Type 3
 ‣ Non-mass enhancement:
   • Distribution:Ductal
   • Internal enhancement:Homogeneous
 ‣ Non-enhancing findings:No
 ‣ Associated features:No
 ‣ Axillary nodes:No

Case summary:

Postmenopausal woman presented with right breast blood-stained nipple discharge, diagnosed as focal short-segment solitary prominent duct with intraductal lesion, BI-RADS category 4B on imaging and as papilloma on histopathology.

Learning points:

  • There is a high risk of metachronous breast carcinoma in a woman who has been diagnosed and treated for breast carcinoma in the other breast. Close surveillance will detect a clinically occult mass as an interval change of developing asymmetry. Ultrasound can delineate changes in the ducts, especially to look for intraductal mass in the clinical setting of bloody nipple discharge under evaluation.

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