The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.

Visitors and news

EMERGENCY: Coronavirus disease (COVID-19) Pandemic

Regular updates on the coronavirus disease (COVID-19) outbreak are available at the WHO website.

New publication: Telemedicine and Cancer Care in Low- and Middle-Income Countries During the SARS-CoV-2 Pandemic

In this commentary, the authors describe the possible roles of telemedicine to improve services across the cancer care continuum in LMICs, challenges of equitable implementation, and possible strategies to overcome these challenges.
View the publication.

Internal Seminar: Estimating the effects of clinical breast examination (CBE) in India: a modeling study in progress

On Friday 3 December, Dr Partha Basu presented the outcomes of the Indian of the randomized controlled trial to evaluate breast cancer screening by clinical breast examination in Trivandrum District, Kerala, India. Sarocha Chootipongchaivat presented on the modelling work that is based on this specific trial. This modelling work is currently ongoing and is a collaboration between the IARC and the Erasmus MC.
Learn more about the Randomized controlled trial to evaluate breast cancer screening by clinical breast examination in Trivandrum District, Kerala, India project.

Postdoctoral Fellowships: Ahmadaye Ibrahim-Khalil

01/12/2021 – 31/05/2022
Dr Ibrahim khalil Ahmadaye is a research scientist holding PhD in molecular biology and clinical epidemiology at Registry Cancer Casablanca (Morocco). Join IARC since September 2019 as a post-doctoral scientist, his work interest includes the Burden of cervical cancer attributable to HIV by age-specific with focus in Sub-Saharan Africa and global burden of Kaposi sarcoma by HIV status. Currently his research focus on the systematic review of therapeutic HPV vaccines in clinical trials mainly phase II/III, evaluating the outcomes on the efficacity in cervical cancer, CIN2, CIN3 lesions and other cancers associated.

Visitor: Dr Sarocha Chootipongchaivat

30/11/2021 – 10/12/2021
Sarocha Chootipongchaivat is a PhD candidate at the Erasmus MC University Medical Center Rotterdam (Netherlands). She is using a microsimulation model (MISCAN-Fadia) to simulate different screening scenarios for various projects related to breast cancer.

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Scientific papers

Yadav K., Ginsburg O., Basu P., Mehrotra R. Telemedicine and Cancer Care in Low- and Middle-Income Countries During the SARS-CoV-2 Pandemic. JCO Glob Oncol. 2021 Sep;7:1633-1638.
PMID: 34860567
Ritchie D., Arbyn M., Basu P., Corbex M., Fidarova E., Ivanuš U., Papi G., Torode J., Zacharopoulou C. Europe's Path to Eliminating Cervical Cancer as a Public Health Problem. Lancet Reg Health Eur. 2022;12:100276.
Miranda-Filho A., Charvat H., Bray F., Migowski A., Cheung L.C., Vaccarella S., Johansson M., Carvalho A.L., Robbins H.A. A modeling analysis to compare eligibility strategies for lung cancer screening in Brazil. EClinicalMedicine. 2021 Nov 1;42:101176.
PMID: 34765952

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