The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.

Visitors and news

New publication: Evaluation of effectiveness, acceptability, and safety of thermal ablation in the treatment of cervical neoplasia in Burundi

Cervical cancer remains a major public health issue in resource-constrained settings. Appropriate management of precancer lesions is a key strategy to achieve cervical cancer elimination. Many low-income countries provide cryotherapy as ablative treatment while thermal ablation (TA) is a more practical and sustainable alternative, although more evidence is needed. This article published in IJC, reports the efficacy of thermal ablation based on the cure rate at 12 months and its potential use in the context of the “screen-and-treat” approach in Burundi.
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CBIG-SCREEN project: field visit to Estonia

16-05-2022 – 19-05-2022
Estonia is the second country visited within the CBIG-SCREEN project to assess the capacity of cervical cancer screening related services. Drs Isabel Mosquera and Keitly Mensah travelled to screening, and colposcopy and treatment facilities in Tallinn and the county of Ida-Viru. This capacity assessment is key to develop the intervention in a later phase of the project.

New publication: Screening technologies for cervical cancer: Overview

This new article reviewed all cervical screening tools and technologies available currently like cytology, liquid based cytology, HPV testing, visual screening tests (e.g. VIA) and discussed about the strategies to manage of women positive any screening test.
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Publication of IARC Handbooks of Cancer Prevention Volume 18: Cervical Cancer Screening

This publication is an important update of the previous IARC Handbook on cervical cancer screening (Volume 10, published in 2005). Volume 18 provides evidence-based evaluations of the effectiveness of five methods of cervical cancer screening in reducing cervical cancer incidence and/or mortality. The Working Group also reviewed the body of evidence and provided conclusive statements on the comparative effectiveness of those screening methods that are established to reduce cervical cancer incidence and/or mortality. In addition, the Working Group provided an updated literature review on the determinants of participation in screening programmes and on emerging techniques, as well as on the different categories of women at differential risk and the surveillance strategies for such women.
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New publication: Evolution of patterns of care for women with cervical cancer in Morocco over a decade

Authors of this article published in BMC Cancer, reported a pattern of care study at two premier-most public-funded oncology centers in Morocco to evaluate delays in care continuum and adherence to internationally accepted treatment guidelines of cervical cancer. This study highlighted there is room for significant improvement through reduction in delays in care and better adherence to internationally recommended treatment guidelines. Increased use of chemoradiation and brachytherapy will improve survival further.
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Scientific papers

Sauvaget C., Bazikamwe S., Lucas E., Ndayikengurukiye A., Harerimana S., Barango P. Evaluation of effectiveness, acceptability, and safety of thermal ablation in the treatment of cervical neoplasia in Burundi. Int J Cancer. 2022 May 14.
PMID: 35567576
Banerjee D., Mittal S., Mandal R., Basu P. Screening technologies for cervical cancer: Overview. Cytojournal. 2022 Mar 29;19:23. doi: 10.25259/CMAS_03_04_2021.
PMID: 35510117
Benider A., Bendahhou K., Sauvaget C., Mrabti H., Selmouni F., Muwonge R., Alaoui L., Lucas E., Chami Y., Abousselham L., Bennani M., Errihani H., Sankaranarayanan R., Bekkali R., Basu P. Evolution of patterns of care for women with cervical cancer in Morocco over a decade. BMC Cancer. 2022 May 2;22(1):479.
PMID: 35501742

All scientific papers

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