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After normal saline |
After acetic acid |
After Lugol’s iodine |
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Nil or transparent | Thin, milky | Distinct, stearin | |
Nil or diffuse | Sharp but irregular, jagged, satellites | Sharp and even, difference in level | |
Fine, regular | Absent | Coarse or atypical vessels | |
< 5 mm | 5-15 mm or 2 quadrants | >15 mm, 3-4 quadrants, or endocervically undefined | |
Brown | Faintly or patchy yellow | Distinctly yellow |
Provisional diagnosis: | Type 2 transformation zone; leukoplakia. |
Management: | Punch biopsy may be obtained from the bigger lesion. Biopsy may be omitted because both lesions are outside the transformation zone. |
Histopathology: | LSIL-HPV changes. |
Comment: | Leukoplakia may be induced by HPV infection. |
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