Home / Training / Manuals / Histopathology of the uterine cervix - digital atlas / Classification TNM/FIGO

Classification TNM/FIGO

Filter by language: English / Français / Portugues / 中文

T — Primary tumour ^1,2

TNM	FIGO
Categories	Stages
TX		Primary tumour cannot be assessed
T0		No evidence of primary tumour
Tis	0	Carcinoma in-situ (preinvasive carcinoma)
T1	I	Cervical carcinoma confined to uterus (extension to corpus should be disregarded)
T1a	IA	Invasive carcinoma diagnosed only by microscopy. All macroscopically visible lesions — even with superficial invasion — are T1b/Stage IB
T1a1	IA1	Stromal invasion no greater than 3.0 mm in depth and 7.0 mm or less in horizontal spread
T1a2	IA2	Stromal invasion more than 3.0 mm and not more than 5.0 mm with a horizontal spread 7.0 mm or less

Note: The depth of invasion should not be more than 5 mm taken from the base of the epithelium, either surface or glandular, from which it originates. The depth of invasion is defined as the measurement of the tumour from the epithelial-stromal junction of the adjacent most superficial epithelial papilla to the deepest point of invasion. Vascular space involvement, venous or lymphatic, does not affect classification.

T1b	IB	Clinically visible lesion confined to the cervix or microscopic lesion greater than T1a2/IA2
T1b1	IB1	Clinically visible lesion 4.0 cm or less in greatest dimension
T1b2	IB2	Clinically visible lesion more than 4 cm in greatest dimension
T2	II	Tumour invades beyond uterus but not to pelvic wall or to lower third of the vagina
T2a	IIA	Without parametrial invasion
T2b	IIB	With parametrial invasion
T3	III	Tumour extends to pelvic wall, involves lower third of vagina, or causes hydronephrosis or non-functioning kidney
T3a	IIIA	Tumour involves lower third of vagina, no extension to pelvic wall
T3b	IIIB	Tumour extends to pelvic wall or causes hydronephrosis or non-functioning kidney
T4	IVA	Tumour invades mucosa of bladder or rectum or extends beyond true pelvis

Note: The presence of bullous oedema is not sufficient to classify a tumour as T4.

M1

IVB

Distant metastasis

N - Regional Lymph Nodes³
NX   Regional lymph nodes cannot be assessed
N0   No regional lymph node metastasis
N1   Regional lymph node metastasis


M - Distant Metastasis
MX   Distant metastasis cannot be assessed
M0   No distant metastasis
M1   Distant metastasis


Stage grouping

Stage 0	Tis	N0	M0
Stage IA	T1a	N0	M0
Stage IA1	T1a1	N0	M0
Stage IA2	T1a2	N0	M0
Stage IB	T1b	N0	M0
Stage IB1	T1b1	N0	M0
Stage IB2	T1b2	N0	M0
Stage IIA	T2a	N0	M0
Stage IIB	T2b	N0	M0
Stage IIIA	T3a	N0	M0
Stage IIIB	T1, T2, T3a	N1	M0
	T3b	Any N	M0
Stage IVA	T4	Any N	M0
Stage IVB	Any T	Any N	M1

1 AJCC (2002). AJCC Cancer Staging Manual. Sixth ed. Springer Verlag: New York.
UICC (2002). TNM classification of malignant tumors. Sixth ed. John Wiley & Sons: New York.

2 A help desk for specific questions about the TNM classification is available at https://www.uicc.org.

3 The regional lymph nodes are the paracervical, parametrial, hypogastric (internal ilial, obturator), common and external iliac, presacral, and lateral sacral nodes.