A digital manual for the early diagnosis of oral neoplasia
Sarcoidosis is an idiopathic multisystemic chronic inflammatory disorder characterized by bilateral hilar lymphadenopathy and noncaseating granulomas in the lungs. Ocular and cutaneous manifestations are common. Oral manifestations include multiple nodular, painless ulcerations of the gingiva, buccal mucosa, labial mucosa and palate. Salivary glands may be involved, leading to a presentation with a dry mouth. An elevated serum level of angiotensin-converting enzyme (ACE) is considered to be the activity marker of the disease. Biopsy and systemic review including blood analysis for ACE level, and chest X-ray will help in the diagnosis.