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The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. For example, the Group significantly contributed to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.


Visitors and news

New publication: “Downstaging in opportunistic breast cancer screening in Brazil: a temporal trend analysis.”

13/05/2019
This new article, published in the BMC Cancer in collaboration with Brazillian School of Medical Sciences of Unicamp, Campinas, examined temporal trends of stage distribution in women with breast cancer diagnosed between 2000 and 2015. The publication highlighted that breast cancer cases are diagnosed mainly at early stages and downstaging has been shown. opportunistic screening may have supported these results.
View the publication.

Meeting: The 2019 Annual Scientific Meeting of the British Society for Colposcopy and Cervical Pathology (BSCCP), Bournemouth, United Kingdom

08/05/2019 – 10/05/2019
Dr Basu has been invited as speaker during the The British Society for Colposcopy and Cervical Pathology (BSCCP) annual scientific meeting and discussed about worldwide initiatives for prevention of cervical cancers and vaccination status in low-middle income countries.

Visit of Dr Yogesh Verma, Sikkim Manipal Institute of Medical Sciences, Gangtok, Sikkim

06/05/2019 – 10/05/2019
Dr Yogesh Verma visited the Screening Group to work on an analysis and preparation of a new manuscript for the extended follow-up of the participants of the HPV vaccine trial to evaluate the effectiveness of one, two, and three doses of quadrivalent HPV vaccine in preventing cervical neoplasia.

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Scientific papers

Vale D.B., Filho C.C., Shinzato J.Y., Spreafico F.S., Basu P., Zeferino L.C. Downstaging in opportunistic breast cancer screening in Brazil: a temporal trend analysis. BMC Cancer. 2019 May 10;19(1):432.
PMID: 31077162
Mahajan M., Naik N., Jain K., Patira N., Prasad S., Mogri S., Muwonge R., Lucas E., Faruq F., Sankaranarayanan R., Iyer S., Basu P. Study of Knowledge, Attitudes, and Practices Toward Risk Factors and Early Detection of Noncommunicable Diseases Among Rural Women in India. J Glob Oncol. 2019 Apr;(5):1-10.
PMID: 30998427
Vale D.B.,Sauvaget C., Murillo R., Muwonge R., Zeferino L.C., Sankaranarayanan R. Correlation of Cervical Cancer Mortality with Fertility, Access to Health Care and Socioeconomic Indicators. Rev Bras Ginecol Obstet. 2019 Mar 25.
PMID: 30912091

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