Chlamydiae Chlamydia trachomatis, obligate intracellular bacteria, may infect the transition zone of uterine cervix. The diagnosis must not be assessed on cytological features originally described as associated with this infection. In fact, these morphologic changes (intracytoplasmic inclusions containing central small coccoid bodies) are not specific and Chlamydia infection may exist without such cellular alterations. Diagnosis is based on molecular tests (Polymerase Chain Reaction or Ligase Chain Reaction). Cytopathology atlas |