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Immunocompromised patients have alterations in phagocytic, cellular or humoral immunity that increase both the risk of infection and the ability to combat infection. Patient immunity may be impaired temporarily or permanently as a result of either an immunodeficiency disease state (congenital or acquired) or induced immunosuppression due to a disease state or its management using cytotoxic, immunosuppressive or radiation therapy (organ transplantation or malignant diseases). Oral candidiasis, herpetic lesions and hairy leukoplakia are more common in immunocompromised individuals.

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