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Central odontogenic myxoma is an odontogenic tumour of mesenchymal origin. Expansion of bone with destruction of the cortex is common. It occurs in the second or third decade of life. A few cases do occur outside the tooth-bearing areas, such as the condyle and condylar neck. The radiographic appearance is that of an expanding radiolucency with honeycomb pattern. Displacement of teeth by the tumour mass is common. Root resorption is not usually present. Surgical excision followed by cautery is the treatment of choice. The prognosis is good, though recurrences have been reported. An exceedingly rare frank malignant form, odontogenic myxosarcoma, has also been reported.

Figure 1: Radiograph of an odontogenic myxoma of the mandible showing the characteristic septa crossing at right angles.
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