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Oral cancer incidence and mortality vary widely across the world; the highest rates are reported from South East Asian countries like India, Pakistan, Bangladesh, Sri Lanka, Taiwan as well as in some parts of Europe, especially France and Hungary Parkin DM, Whelan SL, Ferlay J, Teppo L, Thomas DB, eds., (2002). Cancer Incidence in Five Continents, Lyon, France, IARC Scientific Publications.Curado MP, Edwards B, Shin HR, Storm H, Ferlay J, Heanue M, Boyle P, eds., (2007). Cancer Incidence in Five Continents, Lyon, France, IARC.. The highest incidence is reported in South Karachi, Pakistan. More than 90% of these neoplasms are squamous cell carcinomas arising from the surface epithelium Stewart BW, Kleihues P, eds, (2003). Head and Neck Cancer. In:. World Cancer Report, Lyon, IARC Press, 232-236.; 35% of tumours arise from the minor salivary glands. Sarcomas, malignant melanomas, plasmacytomas and lymphomas are rare. Occasionally metastatic tumours are also reported in the oral cavity.


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