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Cytopathology of the uterine cervix - digital atlas

Low-grade Squamous Intraepithelial Lesion (LSIL)  Rechercher Low-grade Squamous Intraepithelial Lesion (LSIL)

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A and B: LSIL.
LSIL: eosinophilic squamous cells with a perinuclear empty cavity surrounded by cytoplasmic thickening and with moderate nuclear enlargement: typical koilocytes. (obj. 20x)
LSIL: basophilic and a few eosinophilic squamous cells with a perinuclear empty cavity surrounded by cytoplasmic thickening and with moderate nuclear enlargement: typical koilocytes. (obj. 20x)
LSIL: basophilic squamous cells with a perinuclear empty cavity surrounded by cytoplasmic thickening and with moderate nuclear enlargement: typical koilocytes. (obj. 20x)
LSIL: eosinophilic squamous cells with dense cytoplasm, parakeratosis and some typical koilocytes. (obj. 20x)
LSIL: group with a typical koilocyte and two parakeratotic cells. (obj. 20x)
LSIL: typical eosinophilic and basophilic koilocytes associated with some parakeratosis and binucleated cells. (obj. 20x)
Two koilocytes (arrow) in a field containing some cells with an enlarged nucleus or binucleated with parakeratotic features: LSIL. (obj. 10x)
LSIL: koilocyte with an enlarged, hyperchromatic nucleus. (obj. 20x)
LSIL: two eosinophilic koilocytes (arrows) associated with parakeratotic cells. (obj. 20x)
LSIL: eosinophilic koilocyte (arrow) associated with parakeratotic cells. (obj. 20x)
Inflammatory ectocervix: squamous cells with a clear perinuclear halo (arrow) and a nucleus increased in size: Trichomonas vaginalis infection (no visible parasite). No LSIL. (obj. 20x)
Inflammatory ectocervix: squamous cells with a clear perinuclear halo and a nucleus increased in size: Trichomonas vaginalis infection (no visible parasite). No LSIL. (obj. 20x)
Squamous cells with an enlarged nucleus, surrounded by an ill-defined clear halo, associated with parakeratotic cells: LSIL. (obj. 20x)
Squamous cells with an enlarged nucleus, surrounded by an ill-defined clear halo, associated with parakeratotic cells: LSIL. (obj. 20x)
Squamous cells with an enlarged nucleus, surrounded by an ill-defined clear halo, associated with parakeratotic cells: LSIL. (obj. 20x)
Squamous cells with an enlarged nucleus, surrounded by an ill-defined clear halo, associated with atypical parakeratotic cells: LSIL. (obj. 20x)
Typical koilocyte (arrow), eosinophilic cytoplasm, perinuclear empty cavity surrounded by cytoplasmic thickening associated with moderate nuclear enlargement (LSIL). (obj. 10x)
Typical koilocyte (arrow), eosinophilic cytoplasm, perinuclear empty cavity surrounded by cytoplasmic thickening associated with moderate nuclear enlargement (LSIL). (obj. 20x)
Typical koilocytes: eosinophilic squamous cells some of them showing a perinuclear empty cavity surrounded by cytoplasmic thickening associated with moderate nuclear enlargement (LSIL). (obj. 20x)
Typical koilocytes: eosinophilic squamous cells some of them showing a perinuclear empty cavity surrounded by cytoplasmic thickening associated with moderate nuclear enlargement (LSIL). (obj. 20x)
Typical koilocytes: eosinophilic squamous cells some of them showing a perinuclear empty cavity surrounded by cytoplasmic thickening associated with moderate nuclear enlargement (arrow) (LSIL). (obj. 20x)
Typical basophilic koilocyte showing a perinuclear empty cavity surrounded by cytoplasmic thickening associated with distinct nuclear enlargement (LSIL). (obj. 20x)
Typical eosinophilic koilocyte showing a perinuclear empty cavity surrounded by cytoplasmic thickening associated with distinct nuclear enlargement (LSIL). (obj. 20x)
Typical basophilic koilocyte showing a perinuclear empty cavity surrounded by cytoplasmic thickening and an abnormal nucleus, enlarged and hyperchromatic, with an Indian ink chromatin (arrow) (LSIL). (obj. 20x)
Typical koilocyte, with eosinophilic cytoplasm showing a perinuclear empty cavity surrounded by cytoplasmic thickening and nuclear enlargement, hyperchromasia, with an Indian ink chromatin (arrow) (LSIL). (obj. 20x)
Typical basophilic koilocyte showing a double nucleus, accompanied by other slightly atypical cells (LSIL). (obj. 20x)
Basophilic koilocyte showing an abnormal nucleus (arrow), accompanied with other atypical cells, with eosinophilic cytoplasm and hyperchromatic homogenous nuclei (ellipse) (LSIL). (obj. 20x)
Atypical cell (arrow): ASC-US (rule out LSIL). (obj. 20x)
Eosinophilic koilocyte (arrow) showing a perinuclear empty cavity surrounded by cytoplasmic thickening and a bizarre nucleus, enlarged, irregular or double (LSIL). (obj. 20x)
Basophilic koilocyte difficult to detect (arrows) among many intermediate and superficial normal cells (LSIL). (obj. 40x)
Koilocytotic cell of intermediate type, eosinophilic, showing a perinuclear cytoplasmic clearing and an abnormal nucleus, markedly enlarged and hyperchromatic (LSIL). (obj. 20x)
Basophilic koilocytes easily detected among many normal intermediate and superficial squamous cells, in a mildly inflammatory smear (LSIL). (obj. 10x)
Basophilic koilocytes characterized by their enlarged nuclei and more or less typical perinuclear empty cavity surrounded by cytoplasmic thickening (LSIL). (A: obj. 20x, B: obj. 40x)
Basophilic koilocytes among many normal intermediate and superficial squamous cells (LSIL). (A: obj. 20x, B: obj. 40x)
Basophilic koilocytes among many normal intermediate and superficial squamous cells, in a mildly inflammatory smear (LSIL). (A: obj. 20x, B: obj. 40x)
Basophilic koilocytes and normal intermediate and superficial squamous cells (LSIL). (obj. 40x)
Pseudokoilocyte: intermediate squamous cell with a normal nucleus and a perinuclear clearing: artefact. (obj. 20x)
Pseudokoilocyte: the nucleus is pyknotic and there is no optically empty zone. Probably artefact. (obj. 40x)
Pseudokoilocytes (arrows): intermediate and superficial squamous cells with basophilic or eosinophilic cytoplasm, sometimes of navicular type. There is no evidence of LCIL infection. (obj. 20x)
Pseudokoilocytes (dotted line): intermediate and superficial cells with basophilic or eosinophilic cytoplasm, normal or with complete cytoplasmic clearing: probable artefact. (obj. 10x)
Pseudokoilocytes: intermediate and superficial cells with basophilic or eosinophilic cytoplasm, normal or with complete cytoplasmic clearing: probable artefact. (obj. 20x)
Pseudokoilocytes: intermediate and superficial cells with basophilic or eosinophilic cytoplasm, with complete cytoplasmic clearing without nuclear atypia. Artefact. (obj. 20x)
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