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The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.


Visitors and news

Video: Cervical Cancer Awareness Month 2020 with Dr Partha Basu

14/01/2020
Dr Partha Basu, Head of the IARC Screening Group, presents an overview of the worldwide burden of cervical cancer and how IARC is working to eliminate this preventable disease. Current research projects include a project assessing vaccine efficacy, projects to improve access to vaccination and screening, and projects to improve treatment of cervical precancer in low- and middle-income settings. All of these contribute to WHO’s Cervical Cancer Elimination Initiative and provide evidence to support guidelines and policy to. Watch video.

Virtual seminar: Virtual advanced cancer screeening training program for gynecologists on Echo project platform, India

06/01/2020
Dr Partha Basu presented within the framework of the ECHO project, the medical digital Indian platform attended by Indian gynaecologists, a virtual seminar about Preventing Errors on Colposcopy: Limitations of colposcopy and quality assurance.

January is cervical cancer awareness month!

02/01/2020
Throughout January, the International Agency for Research on Cancer (IARC) will mark Cervical Cancer Awareness Month with a series of posts, including tweets, interviews, and infographics. Stay tuned to the IARC website, www.iarc.fr, the IARC Twitter account, @IARCWHO, and the IARC YouTube channel, IARC WHO, during January to learn more about cervical cancer and the worldwide initiative to eliminate this disease as a public health problem. Read the IARC news

New publication: Efficacy and immunogenicity of a single dose of human papillomavirus vaccine compared to no vaccination or standard three and two-dose vaccination regimens: A systematic review of evidence from clinical trials

26/12/2019
The Screening Group is delighted to present the findings of this systematic review published in Vaccine. This review supports the premise that one HPV vaccine dose may be as effective in preventing HPV infection as multi-dose schedules in healthy young women. However, it also highlights the paucity of available evidence from purpose-designed, prospectively-randomised trials. Results from ongoing clinical trials assessing the efficacy and immunogenicity of single-dose HPV vaccination compared to currently-recommended schedules are awaited. View the article.

New publication: Challenges of health promotion and education strategies to prevent cervical cancer in India: A systematic review

24/12/2019
This new systematic review, published in the Journal of Education and Health promotion, studied the challenges of health promotion and education strategies to prevent cervical cancer in India. Observations from this review indicated immediate attention of the public health authority to take appropriate actions to educate and motivate general population toward cervical cancer prevention and to improve the facilities to incorporate the much needed preventive and early detection interventions in India. View the article.

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Scientific papers

Whitworth H.S., Gallagher K.E., Howard N., Mounier-Jack S., Mbwanji G., Kreimer A.R., Basu P., Kelly H., Drolet M., Brisson M., Watson-Jones D. Efficacy and immunogenicity of a single dose of human papillomavirus vaccine compared to no vaccination or standard three and two-dose vaccination regimens: A systematic review of evidence from clinical trials. Vaccine. 2019 Dec 20. pii: S0264-410X(19)31659-7.
PMID: 31870572
Thulaseedharan J.V., Frie K.G., Sankaranarayanan R. Challenges of health promotion and education strategies to prevent cervical cancer in India: A systematic review. J Educ Health Promot. 2019 Nov 29;8:216.
PMID: 31867380
Bhatla N., Singhal S., Saraiya U., Srivastava S., Bhalerao S., Shamsunder S., Chavan N., Basu P., Purandare C.N. on behalf of FOGSI Expert group. Screening and management of preinvasive lesions of the cervix: Good clinical practice recommendations from the Federation of Obstetrics and Gynaecologic Societies of India (FOGSI). J Obstet Gynaecol Res. 2019 Dec 9. doi: 10.1111/jog.14168.
PMID: 31814222

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