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The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.


Visitors and news

EMERGENCY: Coronavirus disease (COVID-19) Pandemic

16/03/2020
Regular updates on the coronavirus disease (COVID-19) outbreak are available at the WHO website.

Kick-off meeting: The development and evaluation of an artificial intelligence (AI) image recognition device to improve cervical pre-cancer screening and management in low- and middle-income countries (SAVE-Cervix)

25/10/2021
In collaboration with the All India Institute of Medical Sciences (New Delhi, India), the Cancer Institute (WIA) Chennai (Chennai, India), the Chittaranjan National Cancer Institute (CNCI) (Kolkata, India) and the National Cancer Institute (Bangkok, Thailand), the Early Detection, Prevention & Infections Branch/IARC is officially launching today the SAVE-Cervix project to facilitate the development and evaluation of an artificial intelligence (AI) image recognition device to improve cervical pre-cancer screening and management in low- and middle-income countries. View the SAVE-Cervix research summary page.

Meeting: Beating liver cancer in Europe – the empowerment of prevention and early detection

22/10/2021
Dr Partha Basu, Deputy Head of Cancer Early Detection and Prevention Branch, highlights policies, new cancer screening scheme, and actions urgently needed to fight liver cancer in European Union within the framework of this High-level event on Beating liver cancer in Europe. This advocacy event was organized under the patronage of the Slovenian presidency of the Council of the European Union, the European Association for Study of the Liver (EASL) and the European Liver Patients’ Association (ELPA).
View the meeting information.

New video: how breast cancer care was improved in Morocco?

21/10/2021
In this video, Dr Partha Basu, describes improvements and gaps in breast cancer screening and treatment in Morocco between 2008 and 2017. The study involved more than 2000 patients with breast cancer and documented the changing patterns of care over a decade, from 2008 to 2017, including temporal variations in breast cancer characteristics, the level of improvement in access to cancer diagnosis and treatment over time, the variations in practices related to breast cancer treatment, and the time trend of disease-free survival for these patients. View the video.

New publication: Patterns of care for women with breast cancer in Morocco: an assessment of breast cancer diagnosis, management, and survival in two leading oncology centres

21/10/2021
This new publication summarizes the outcomes of a patterns-of-care study implemented by IARC in collaboration with the Ministry of Health of the Kingdom of Morocco and the Lalla Salma Foundation for Cancer Prevention and Treatment, to assess how far state-of-the-art cancer diagnostics and therapy have been disseminated into routine oncology practice in Morocco. The findings highlight the improvements in breast cancer care that occurred in Morocco as a result of pragmatic policies and systematic planning by the Moroccan Ministry of Health. Recommendations for strengthening breast cancer care in Morocco are also included in the publication. View the publication, the IARC news and the project page.

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Scientific papers

Bhatla N., Aoki D., Sharma D.N., Sankaranarayanan R. Cancer of the cervix uteri: 2021 update. Int J Gynaecol Obstet. 2021 Oct;155 Suppl 1:28-44.
PMID: 34669203
Basu P., Malvi S.G., Joshi S., Bhatla N., Muwonge R., Lucas E., Verma Y., Esmy P., Poli U.R.R., Shah A., Zomawia E., Pimple S., Jayant K., Hingmire S., Chiwate A., Divate U., Vashist S., Mishra G., Jadhav R., Siddiqi M., Sankaran S., Prabhu P.R., Kannan T.P.R.A., Varghese R., Shastri S.S., Anantharaman D., Gheit T., Tommasino M., Sauvaget C., Pillai M.R., Sankaranarayanan R. Vaccine efficacy against persistent human papillomavirus (HPV) 16/18 infection at 10 years after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre, prospective, cohort study. Lancet Oncol, Published online 8 October 2021.
PMID: 34634254
Ringborg U., Berns A., Celis J.E., Heitor M., Tabernero J., Schuz J., Baumann M., Henrique R., Aapro M., Basu P., Beets-Tan R., Besse B., Cardoso F., Carneiro F., van den Eede G., Eggermont A., Frohling S., Galbraith S., Garralda E., Hanahan D., Hofmarcher T., Jonsson B., Kallioniemi O., Kasler M., Kondorosi E., Korbel J., Lacombe D., Carlos Machado J., Martin-Moreno J.M., Meunier F., Nagy P., Nuciforo P., Oberst S., Oliveiera J., Papatriantafyllou M., Ricciardi W., Roediger A., Ryll B., Schilsky R., Scocca G., Seruca R., Soares M., Steindorf K., Valentini V., Voest E., Weiderpass E., Wilking N., Wren A., Zitvogel L. The Porto European Cancer Research Summit 2021. Mol Oncol. 2021 Sep 13. doi: 10.1002/1878-0261.13078.
PMID: 34515408

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