The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.

Visitors and news

EMERGENCY: Coronavirus disease (COVID-19) Pandemic

Regular updates on the coronavirus disease (COVID-19) outbreak are available at the WHO website.

Kick-off meeting: Artificial intelligence-assisted decision-making to improve women’s participation to cervical cancer screening in Occitanie Region-France

In collaboration with the Centre Régional de Coordination de Dépistage des Cancers d’Occitanie (CRCDC-Occitanie) and The “Université de Bretagne Occidentale”, The Early Detection, Prevention & Infections Branch/IARC is officially launching today the AppDate-You project to tackle the burden and inequalities in cervical cancer screening. The project aims to evaluate the impact of artificial intelligence-assisted decision-making to improve women’s knowledge and participation to cervical cancer screening in Occitanie Region-France. This project is funded by the French Institut National du Cancer (INCA).

Job opportunity: Scientist (cancer screening inequalities/Latin America)

A temporary scientist position is opened for a public health/biomedical researcher in the Early Detection, Prevention and Infections Branch (EPR). The creation of this position is in response to a funded initiative focusing on social inequalities related to cancer screening participation in Latin America. The project contains a major component of coordination and networking with stakeholders, and offers excellent opportunities to attract additional competitive funding. View the job vacancy.

New publication: Cancer screening in the Coronavirus pandemic era- adjusting to a new situation

The present article published in JCO Gobal Oncology discusses the challenges to cancer screening implementation in the pandemic environment, suggesting ways to optimize services for breast, cervical, and colorectal cancer screening. Authors provides guidance on reorganization of screening policies, governance, implementation, and program monitoring.
View the article

Kick-off meeting: CBIG-SCREEN, a collaborative European-wide effort to tackle inequalities in cervical cancer screening

The International Agency for Research on Cancer (IARC) is participating in a new project within the framework of the European Union Horizon2020 research and innovation programme. Today is the official kick-off of the CBIG-SCREEN project – a collaborative European-wide effort to tackle inequalities in cervical cancer screening. The project will thus create a Europe-wide knowledge framework around barriers to cervical cancer screening and generate policies, programmes, communications and other required services to meet the needs of these underserved sub-populations of women with inherent high-risk of cervical cancer and low (perceived) access to proper healthcare routes.
View the press release, view the IARC news, view the CBIG-SCREEN project summary, and view the CBIG-SCREEN project website.

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Scientific papers

Simoens C., Gorbaslieva I., Gheit T., Holzinger D., Lucas E., Ridder R., Rehm S., Vermeulen P., Lammens M., Vanderveken O.M., Kumar R.V., Gangane N., Caniglia A., Maffini F., Rubio M.B.L. , Anantharaman D., Chiocca S., Brennan P., Pillai M.R., Sankaranarayanan R., Bogers J., Pawlita M., Tommasino M., Arbyn M., HPV-AHEAD study group. HPV DNA genotyping, HPV E6*I mRNA detection, and p16 INK4a/Ki-67 staining in Belgian head and neck cancer patient specimens, collected within the HPV-AHEAD study. Cancer Epidemiol. 2021 Apr 8;72:101925.
PMID: 33839457
Basu P., Alhomoud S., Taghavi K., Carvalho A.L., Lucas E., Baussano I. Cancer Screening in the Coronavirus Pandemic Era: Adjusting to a New Situation. JCO Glob Oncol. 2021 Mar;7:416-424.
PMID: 33784177
Matos L.L., Forster C.H.Q., Marta G.N., Castro Junior G., Ridge J.A., Hirata D., Miranda-Filho A., Hosny A., Sanabria A., Gregoire V., Patel S.G., Fagan J.J., D'Cruz A.K., Licitra L., Mehanna H., Hao S.P., Psyrri A., Porceddu S., Galloway T.J., Golusinski W., Lee N.Y., Shiguemori E.H., Matieli J.E., Shiguemori A.P.A.C., Diamantino L.R., Schiaveto L.F., Leao L., Castro A.F., Carvalho A.L., Kowalski L.P. The hidden curve behind COVID-19 outbreak: the impact of delay in treatment initiation in cancer patients and how to mitigate the additional risk of dying-the head and neck cancer model. Cancer Causes Control. 2021 Mar 11:1-13.
PMID: 33704627

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