The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.

Visitors and news

EMERGENCY: Coronavirus disease (COVID-19) Pandemic

Regular updates on the coronavirus disease (COVID-19) outbreak are available at the WHO website.

New publication: The Quebec mixed-schedule HPV vaccination policy will maximize public health gain

In this commentary published in HPVWORLD, Dr Partha Basu discusses the Quebec's Mixed HPV vaccination schedule introduction.
View the article.

New publication: Feasibility, Acceptability, and Efficacy of a Community Health Worker-Driven Approach to Screen Hard-to-Reach Periurban Women Using Self-Sampled HPV Detection Test in India

This article published in JCO Global Oncology reports the evaluation of the feasibility, acceptability, and efficacy of implementing an HPV self-sampling–based approach to screen a socioeconomically disadvantaged, unscreened population with support from community health workers (CHWs). Authors concluded CHW-driven self-sampling for HPV testing is feasible, well-accepted, and effective for screening unscreened hard-to-reach women. The screen-and-treat approach can ensure linkage between screening and treatment. View the article.

New publication: Diagnostic performance of automated breast ultrasound and handheld ultrasound in women with dense breasts

Authors reported the outcomes of this cross-sectional multicentre clinical research study organized in China. They evaluated the diagnostic performance of automated breast ultrasound system (ABUS) and handheld ultrasound (HHUS) in Chinese women with dense breasts, both in combination with mammography and separately. In this study, both ABUS and HHUS as adjuncts to mammography significantly improved the breast cancer detection rate in women with dense breasts. Given the high prevalence of dense breasts and the multiple advantages of ABUS over HHUS, such as less operator dependence and reproducibility, ABUS showed great potential for use in breast cancer early detection, especially in resource-limited areas. View the article.

IFCPC-IARC training course in colposcopy and the prevention of cervical cancer - theory and image case only

Registration is now open for trainees wishing to attend the online edition of the IFCPC-IARC Training Course in Colposcopy and the Prevention of Cervical Cancer. Visit the IFCPC website for more details and registration form. This is an exciting new opportunity for medical personnel wishing to train in colposcopy and prevention of cervical cancer with 30 lectures by world renowned experts in the field. The course provides comprehensive, multimodal training incorporating theoretical knowledge and image recognition. Course commences from 20th April 2020. See also the online training course brochure.

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Scientific papers

Almonte M., Murillo R., Sanchez G.I., Gonzalez P., Ferrera A., Picconi M.A., Wiesner C., Cruz-Valdez A., Lazcano-Ponce E., Jeronimo J., Ferreccio C., Kasamatsu E., Mendoza L., Rodriguez G., Calderon A., Venegas G., Villagra V., Tatti S., Fleider L., Teran C., Baena A., Hernandez M.L., Rol M.L., Lucas E., Barbier S., Ramirez A.T., Arrossi S., Rodriguez M.I., Gonzalez E., Celis M., Martinez S., Salgado Y., Ortega M., Beracochea A.V., Perez N., Rodriguez de la Pena M., Ramon M., Hernandez-Nevarez P., Arboleda-Naranjo M., Cabrera Y., Salgado B., Garcia L., Retana M.A., Colucci M.C., Arias-Stella J., Bellido-Fuentes Y., Bobadilla M.L., Olmedo G., Brito-Garcia I., Mendez-Herrera A., Cardina L., Flores B., Penaranda J., Martinez-Better J., Soilan A., Figueroa J., Caserta B., Sosa C., Moreno A., Mural J., Doimi F., Gimenez D., Rodriguez H., Lora O., Luciani S., Broutet N., Darragh T., Herrero R. Multicentric study of cervical cancer screening with human papillomavirus testing and assessment of triage methods in Latin America: the ESTAMPA screening study protocol. BMJ Open 2020;10:e035796.
PMID: 32448795
Poli U.R., Muwonge R., Bhoopal T., Lucas E., Basu P. Feasibility, Acceptability, and Efficacy of a Community Health Worker-Driven Approach to Screen Hard-to-Reach Periurban Women Using Self-Sampled HPV Detection Test in India. JCO Glob Oncol. 2020 Apr;6:658-666.
PMID: 32343627
Jia M., Lin X., Zhou X., Yan H., Chen Y., Liu P., Bao L., Li A., Basu P., Qiao Y., Sankaranarayanan R. Diagnostic performance of automated breast ultrasound and handheld ultrasound in women with dense breasts. Breast Cancer Res Treat. 2020 Apr 27.
PMID: 32338323

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