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The core function of the Screening Group (SCR) at IARC is to provide data on the accuracy, reproducibility, efficacy, benefits, harmful effects, and cost-effectiveness of various early detection interventions for breast, cervical, colorectal, and oral cancers, among others, in reducing deaths and improving patients’ quality of life in various settings. These data can then be used to inform and improve the rational use of health-care resources. The Group’s ultimate objective is to guide the development of public health policies for implementing screening in a variety of health-care settings, in particular in low- and middle-income countries (LMICs).

SCR conducts field studies in LMICs to evaluate various early detection methods for breast, cervical, colorectal, and oral cancer control. These initiatives also address the means by which screening services could be scaled up through local public health services. SCR develops various training resources to catalyse and augment capacity building in close collaboration with national institutions and government health services. Through its research programme, SCR generates scientific evidence to support the development of resource-appropriate early detection policies and health systems for the delivery of effective early services. The Cancer Screening in 5 Continents (CanScreen5) project of the Group aims to collect information on characteristics and performance of cancer screening programmes around the world and disseminate such information for informed decision making in cancer screening programmes. For example, the Group significantly contributed also to the evaluation of the safety and efficacy of less than three doses of the HPV vaccine in protecting against cervical cancer.


Visitors and news

New publication: Thermal ablation versus cryotherapy or loop excision to treat women positive on visual inspection with acetic acid test: pilot phase of a randomised controlled trial

14/11/2019
The Screening Group is delighted to present the early results of a new pilot study done in Lusaka, Zambia and published in the Lancet Oncology. This study compared three different treatments in women who were eligible for ablative therapy for cervical pre-cancer (crytherapy, LLETZ and thermal ablation). The results of the pilot study provide valuable evidence to inform the recently published WHO recommendation for using thermal ablation to treat cervical pre-cancers. Read the article, the commentary, the IARC News and the WHO guidelines for the use of thermal ablation for cervical pre-cancer lesions.

Video: Thermal ablation versus cryotherapy or loop excision to treat women positive for cervical precancer

14/11/2019
Dr Partha Basu, Head of the IARC Screening Group and an author of the new study published in The Lancet Oncology, described the trial, the new innovative thermal ablation device to treat cervical pre-cancers and the promising early results.
Watch video.

Video: Thermal ablation versus cryotherapy or loop excision to treat women positive for cervical precancer

14/11/2019
Dr Walter Prendiville, Senior visiting scientist at IARC Screening Group, an author of the new study published in The Lancet Oncology, and a key advisor in the development of the thermal ablation device, described why the device was developed and the advantages it offers compared with current treatment options.
Watch video.

Video: What should be the HPV vaccine strategy for India with Dr Rengaswamy Sankaranarayanan

10/11/2019
Dr Rengaswamy Sankaranarayanan, former Screening Group head and currently senior visiting scientist discussed about the HPV vaccine strategy for India in this video recorded by ecancer during the "Choosing Wisely: Value added cancer care for India" conference the 15-16 October 2019 in All India Institute of Medical Science, New Delhi, India.
Watch video.

Third CICAMS-IARC joint training course on cancer prevention and control, Shenzhen, China

04/11/2019 – 08/11/2019
The Screening Group co-organized this third training course in collaboration with the Cancer Institute/Hospital of the Chinese Academy of Medical Sciences (CICAMS) for the ASEAN countries, with 41 attendees and faculty members from Brunei Darussalam, Cambodia, China, Indonesia, Lao People’s Democratic Republic, Malaysia, Myanmar, Philippines, Singapore, Thailand, and Viet Nam.
View the IARC News and learn more about the CIACMS-IARC joint training course.

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Scientific papers

Pinder L.F., Parham G.P., Basu P., Muwonge R., Lucas E., Nyambe N., Sauvaget C., Mwanahamuntu M.H., Sankaranarayanan R., Prendiville W. Thermal ablation versus cryotherapy or loop excision to treat women positive for cervical precancer on visual inspection with acetic acid test: pilot phase of a randomised controlled trial. Lancet Oncol, Published online 13 November 2019;
PMID:
Sankaranarayanan R., Basu P., Kaur P., Bhaskar R., Singh G.B., Denzongpa P., Grover R.K., Sebastian P., Saikia T., Oswal K., Kanodia R., Dsouza A., Mehrotra R., Rath G.K., Jaggi V., Kashya S., Kataria I., Hariprasad R., Sasieni P., Bhatla N., Rajaraman P., Trimble E.L., Swaminathan S., Purushotham A. Current status of human papillomavirus vaccination in India's cervical cancer prevention efforts. Lancet Oncol. 2019 Nov;20(11):e637-e644.
PMID: 31674322
Basu P., Hutubessy R., Broutet N. Cervical cancer: WHO called for elimination, not eradication. BMJ. 2019 Sep 26;366:l5668.
PMID: 31558438

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