Atlas of Colposcopy: Principles and Practice / Activity 6

Case

Early and advanced cancers / Adenocarcinoma
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Age: 43
HPV status: Positive

Speculum examination

After normal saline

After normal saline with green filter

After acetic acid

After acetic acid with green filter

After Lugol’s iodine

Colposcopy report (2011 IFCPC nomenclature):
/ Post-treatment consequence / Endometriosis

General assessment
Adequacy:

Squamocolumnar junction visibility:

Transformation zone:

Normal colposcopic findings
Original squamous epithelium:

Columnar epithelium:

Metaplastic squamous epithelium:

Deciduosis in pregnancy:

Abnormal colposcopic findings
General principles
Position and size

Location of the lesion:

Location of the lesion by clock position:
No. of quadrants:

% of cervix:

Grade 1 (minor)

Grade 2 (major)

Non-specific

Suspicious for invasion

Miscellaneous finding

Swede score:

Swede score 0 1 2
Aceto uptake Nil or transparent Thin, milky Distinct, stearin
Margins Nil or diffuse Sharp but irregular, jagged, satellites Sharp and even, difference in level
Vessels Fine, regular Absent Coarse or atypical vessels
Lesion size < 5 mm 5-15 mm or 2 quadrants >15 mm, 3-4 quadrants, or endocervically undefined
Iodine uptake Brown Faintly or patchy yellow Distinctly yellow
Final Swede score: 10

Case Summary
Provisional diagnosis: Type 2 transformation zone; high-grade squamous intraepithelial lesion (HSIL) with suspected adenocarcinoma in situ.
Management: LLETZ (type 3 excision) with endocervical curettage. Cold-knife conization can also be done.
Histopathology: Adenocarcinoma in situ.
Comment: Glandular lesions often coexist with high-grade squamous lesions. A dense acetowhite area over the columnar epithelium is characteristic of a glandular lesion.

Swede score	0	1	2
Aceto uptake	Nil or transparent	Thin, milky	Distinct, stearin
Margins	Nil or diffuse	Sharp but irregular, jagged, satellites	Sharp and even, difference in level
Vessels	Fine, regular	Absent	Coarse or atypical vessels
Lesion size	< 5 mm	5-15 mm or 2 quadrants	>15 mm, 3-4 quadrants, or endocervically undefined
Iodine uptake	Brown	Faintly or patchy yellow	Distinctly yellow

Provisional diagnosis:	Type 2 transformation zone; high-grade squamous intraepithelial lesion (HSIL) with suspected adenocarcinoma in situ.
Management:	LLETZ (type 3 excision) with endocervical curettage. Cold-knife conization can also be done.
Histopathology:	Adenocarcinoma in situ.
Comment:	Glandular lesions often coexist with high-grade squamous lesions. A dense acetowhite area over the columnar epithelium is characteristic of a glandular lesion.