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Cancer control
| Study sites: | Not applicable |
| Principal investigator (PI) from IARC: | P. Basu |
| PIs from collaborating institutions: |
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| Start date: | 2017 |
| Closure date: | Ongoing |
| Objectives: | The purpose of the project is to collect standardized information on the characteristics and performance of cancer screening programmes around the world, and to disseminate that information to enable improved programme management and informed policy, strengthen health information systems, and support research. Systematic, standardized reporting of programme characteristics and quality indicators will be of great value not only to the participating programme managers to improve programme quality, but also to others striving to make their programmes more effective. CanScreen5 will be an online portal for the collection, analysis, and dissemination of information on cancer screening programmes and activities in countries around the world, with the core objective of motivating and enabling countries to collect and use cancer screening data in a consistent manner. |
| Methodology: |  The project methodology will be based on the IARC Screening Group’s recent experience reporting the status of implementation and performance of breast, cervical, and colorectal cancer screening programmes in the 28 member states of the European Union (“Cancer Screening in the European Union”, 2017). A network of collaborators and institutions will be formed in order to access qualitative and quantitative information on cancer screening programmes in various countries. A protocol for standardized data collection will be developed, along with data collection tools. A web-based platform will be created for data collection and dissemination of the analysed data. The IARC Screening Group will serve as the project secretariat, and the project will be implemented in phases. Quality checks will be carried out to ensure that the data collected from each country meet a defined set of minimum standards. Ethical issues, protection of data privacy, and regulatory issues that apply to sharing data will be thoroughly reviewed. Visit the CanScreen5 website. |
| Funding: | Intramural funding from IARC; support from the Pan American Health Organization (PAHO) |
| Study sites: | Morocco: Casablanca, Fez, Rabat |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: |
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| Start date: | 2016 |
| Closure date: | Ongoing |
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| Methodology: | The evaluation will be based on information obtained through in-depth interviews of the key functionaries of the programme, focus group discussions with various categories of service providers, and supervisory visits to randomly selected facilities offering screening and diagnostic services. | Publications: | Basu P., Selmouni F., Belakhel L., Sauvaget C., Abousselham L., Lucas E., Muwonge R., Sankaranarayanan R., Khazraji Y.C. Breast Cancer Screening Program in Morocco: Status of implementation, organization and performance. Int J Cancer. 2018 Jul 14. PMID: 30006933 Selmouni F., Zidouh A., Belakhel L., Sauvaget C., Bennani M., Khazraji Y.C., Benider A., Wild C.P., Bekkali R., Fadhil I., Sankaranarayanan R. Tackling cancer burden in low-income and middle-income countries: Morocco as an exemplar. Lancet Oncol. 2018 Feb;19(2):e93-e101. PMID: 29413484 Selmouni F., Belakhel L., Sauvaget C., Abousselham L., Lucas E., Muwonge R., Sankaranarayanan R., Khazraji Y.C., Basu P. Evaluation of the national cervical cancer screening program in Morocco: achievements and challenges. J Med Screen. 2019 Jan 16:969141318824627. PMID: 30651034 |
| Funding: | Lalla Salma Foundation for Cancer Prevention and Treatment |
| Study sites: | imPACT Reviews have been carried out in: Algeria (2015), Bangladesh (2013), Benin (2013), Bosnia and Herzegovina (2015), Botswana (2013), Burundi (2017), Cambodia (2013), Croatia (2014), Fiji (2014), Georgia (2014), Kyrgyzstan (2015), Lebanon (2013), Madagascar (2015), Malaysia (2013), Mauritania (2012), Mongolia (2011), Myanmar (2015), Nepal (2012), Pakistan (2013), Rwanda (2014), Tunisia (2013), Viet Nam (2015) |
| PIs from collaborating institutions: | The International Atomic Energy Agency (IAEA), WHO, IARC |
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| Start date: | 2011 |
| Closure date: | Ongoing |
| Objectives: |
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| Methodology: | Assessment is carried out through meetings with the focal point at the Ministry of Health, field visits at the three levels of care, discussions with health-care providers, and interaction with the local officers of the various health-related UN agencies (mainly WHO) and IAEA country offices. |
| Funding: | International Atomic Energy Agency (IAEA) Programme of Action for Cancer Therapy (PACT) |
| Study sites: | Dhaka, Bangladesh |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: | Dr Ashrafun Nessa, Bangabandhu Sheikh Mujib Medical University (BSMMU) |
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| Start date: | 2006 |
| Closure date: | Ongoing |
| Objectives: | To provide technical support to help organize a screening programme for cervical cancer prevention in Bangladesh |
| Methodology: | The following technical support is provided:
| Publications: | Nessa A., Hussain M.A., Rahman J.N., Rashid M.H., Muwonge R., Sankaranarayanan R. Screening for cervical neoplasia in Bangladesh using visual inspection with acetic acid. Int J Gynaecol Obstet. 2010;111(2):115-8. PMID: 20674919 Sankaranarayanan R., Bhatla N., Gravitt P.E., Basu P., Esmy P.O., Ashrafunnessa K.S., Ariyaratne Y., Shah A., Nene B.M. Human papillomavirus infection and cervical cancer prevention in India, Bangladesh, Sri Lanka and Nepal. Vaccine. 2008;26(Suppl 12):M43-M52. PMID: 18945413 |
| Study sites: | National Cancer Institute / National Cancer Control Programme, Sri Lanka |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: | Suraj Perera |
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| Start date: | 2006 |
| Closure date: | Ongoing |
| Objectives: | To provide technical support to the national cancer control programme |
| Methodology: | The following technical support is provided:
| Publications: | Sankaranarayanan R., Bhatla N., Gravitt P.E., Basu P., Esmy P.O., Ashrafunnessa K.S., Ariyaratne Y., Shah A., Nene B.M. Human papillomavirus infection and cervical cancer prevention in India, Bangladesh, Sri Lanka and Nepal. Vaccine. 2008;26(Suppl 12):M43-M52. PMID: 18945413 |
| Study sites: | Thailand |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: | Weerawut Imsamran, Suleeporn Sangrajrang, Pattarawin Attasara, National Cancer Institute, Bangkok, Thailand |
| Map: |  |
| Start date: | 2006 |
| Closure date: | Ongoing |
| Objectives: | To provide technical support to the national cancer control programme |
| Methodology: | The following technical support is provided:
| Publications: | Deerasamee S., Srivatanakul P., Sriplung H., Nilvachararung S., Tansuwan U., Pitakpraiwan P., Kaewkungwal J., Singhasivanon P., Nimnakorn P., Sankaranarayanan R. Monitoring and evaluation of a model demonstration project for the control of cervical cancer in Nakhon Phanom province, Thailand. Asian Pac J Cancer Prev. 2007 Oct-Dec;8(4):547-56. PMID: 18260727 Khuhaprema T., Attasara P., Srivatanakul P., Sangrajrang S., Muwonge R., Sauvaget C., Sankaranarayanan R. Organization and evolution of organized cervical cytology screening in Thailand. Int J Gynaecol Obstet. 2012;118(2):107-11. PMID: 22613493 |
| Study sites: | Morocco: Casablanca, Fez, Marrakech, Rabat |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: |
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| Map: |  |
| Start date: | 2016 |
| Closure date: | Ongoing |
| Objectives: |
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| Methodology: | The basis of the study is a face-to-face qualitative questionnaire survey. |
| Funding: | Lalla Salma Foundation for Cancer Prevention and Treatment |
| Study sites: | Ministry of Health, Morocco |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: |
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| Map: |  |
| Start date: | 2014 |
| Closure date: | Ongoing |
| Objectives: | To provide technical support to improve the current information system for monitoring the breast and cervical cancer screening programme |
| Methodology: | We propose for the Breast and Cervical Cancer Early Detection Programme
| Publications: | Basu P., Selmouni F., Belakhel L., Sauvaget C., Abousselham L., Lucas E., Muwonge R., Sankaranarayanan R., Khazraji Y.C. Breast Cancer Screening Program in Morocco: Status of implementation, organization and performance. Int J Cancer. 2018 Jul 14. PMID: 30006933 Selmouni F., Zidouh A., Belakhel L., Sauvaget C., Bennani M., Khazraji Y.C., Benider A., Wild C.P., Bekkali R., Fadhil I., Sankaranarayanan R. Tackling cancer burden in low-income and middle-income countries: Morocco as an exemplar. Lancet Oncol. 2018 Feb;19(2):e93-e101. PMID: 29413484 |
| Funding: | United Nations Population Fund (UNFPA) Morocco |
| Study sites: | Low- and middle-income countries |
| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| Start date: | 2014 |
| Closure date: | 2016 |
| Objectives: | To establish an observational prospective cohort of women receiving cervical cancer screening in selected countries implementing cervical cancer screening programmes in order to estimate key process and outcome indicators not currently measurable through routine information systems, and also to validate the tools for data collection |
| Methodology: | 
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| Funding: | CDC Foundation, USA |
| Study sites: |
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| Principal investigator (PI) from IARC: | R. Sankaranarayanan |
| PIs from collaborating institutions: | R. Swaminathan, H. Brenner, B. Ganesh, A. Mathew, M. Hakama, K. Jayant |
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| Start date: | 1990 |
| Closure date: | 2011 |
| Objectives: | The dearth of reliable survival statistics from developing countries was very evident until the mid-1990s. This prompted IARC to undertake a project that facilitated hands-on training and thereby the transfer of knowledge and technology on cancer survival analysis to researchers from the participating population-based cancer registries, which culminated in the publication of the first volume of the IARC Scientific Publication on cancer survival in developing countries in 1998. The present study is the second in the series, with wider geographical coverage, and is based on data from 27 registries in 14 countries in Africa, Asia, the Caribbean, and Central America. The calendar period of registration of incident cases for the present study ranges between 1990 and 2001. Data on 564 606 cases of 1–56 cancer sites from different registries are reported. Data from 11 registries were used to determine survival trends and data from 17 registries for reporting survival by clinical extent of disease. The publication includes chapters on each registry and general chapters on methodology, the database, and an overview. Comparative statistics on cancer survival by participating registry or by cancer site are also available online in the form of tables and graphs (https://survcan.iarc.fr). |
| Methodology: | Population-based cancer survival data (a key indicator for monitoring progress against cancer) are not widely available in low- and middle-income countries. Cancer-specific survival of patients diagnosed in 1990–2001, and followed-up to 2003 in 25 population-based cancer registries from 12 countries in sub-Saharan Africa, Central America, and Asia were analysed by actuarial methods. Visit the SurvCan website | Publications: | Sankaranarayanan R., Swaminathan R. Cancer survival in Africa, Asia, the Caribbean and Central America. Lyon: International Agency for Research on Cancer. IARC Scientific Publication No. 162; 2011. Visit the book’s IARC Publications page Sankaranarayanan R., Swaminathan R., Brenner H., Chen K., Chia K.S., Chen J.G., Law S.C., Ahn Y.O., Xiang Y.B., Yeole B.B., Shin H.R., Shanta V., Woo Z.H., Martin N., Sumitsawan Y., Sriplung H., Barboza A.O., Eser S., Nene B.M., Suwanrungruang K., Jayalekshmi P., Dikshit R., Wabinga H., Esteban D.B., Laudico A., Bhurgri Y., Bah E., Al-Hamdan N. Cancer survival in Africa, Asia, and Central America: a population-based study. Lancet Oncol. 2010;11(2):165-73. PMID: 20005175 |
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