A digital manual for the early diagnosis of oral neoplasia
Malignant transformation of oral lesions
Figure 9: Nodular leukoplakia with malignant transformation. Note the pin head-sized nodules scattered on an erythematous base. The margins of the lesion are diffuse, and the granular area (arrow) seen anteriorly is clinically suspicious of malignancy. Histopathological examination of the granular area was suggestive of well-differentiated squamous cell carcinoma.