HSIL: parabasal cells with nuclear enlargement, irregular nuclear outlines and coarse chromatin. A LSIL could be discussed because of the abundance of cytoplasm and the perinuclear clearing. (obj. 20x)
picture quality:On a scale of 1 to 5 stars, with 5 stars being the best quality
While it\'s true that the cell on the bottom left has features of ASC-US/LSIL, the two cells in the middle are more remarkably parabasal sized cells, putting you into the category of ASC-H or HSIL. Since the nucleus shows irregular features, up the call, and this will immediately bring you to HSIL. Remember, ASC-US & LSIL occur in intermediate/superficial cells. The cells in the middle are much, much smaller.